The DNA damage response (DDR) constitutes a multifaceted network of sensors, transducers and effectors that preserves genome integrity by detecting and repairing lesions arising from endogenous ...

Cohesin is a key regulator of three-dimensional genome organization, contributing to gene regulation, recombination, DNA repair and chromosome segregation. Like other members of the evolutionary ...

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria. The ...

Five years ago, scientists watched in wonder as synthetic bacteria grew and split into daughter cells. The bacteria’s extremely stripped-down genome still supported its entire life cycle. It was a ...