Researchers have found a new enzyme, taken from Flavobacterium akiainvivens, that has a much broader specificity than the current leading alternatives. This analysis resulted in the identification of ...

Enzymes are regarded as the key to sustainable chemistry. Despite major advances in protein design, creating artificial ...

A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

FMI researchers have developed a new tool that maps how proteases—enzymes that process proteins—cut their targets. This innovation offers new insight into the highly selective nature of proteases, ...

C2′-halogenation has been recognized as an essential modification to enhance the drug-like properties of nucleotide analogs. The direct C2ʹ-halogenation of the nucleotide ...

A new protein-design workflow turns inactive artificial scaffolds into efficient enzymes, opening paths to greener chemistry and biotech.

Enzymes are powerful catalysts in nature, enabling the sustainable and efficient synthesis of complex biomolecules. The remarkable efficiency of enzymes arises from the intricately organized and ...

Enzymes are biological catalysts that speed up chemical reactions in living organisms. They are essential for life, as they play a crucial role in various biological processes, such as digestion, ...

In a new study published in Nature titled, “Custom CRISPR-Cas9 PAM variants via scalable engineering and machine learning,” researchers from Massachusetts General Hospital (MGH) and Harvard Medical ...